Comprehensive Survey of Combinatorial Library Synthesis: 1998
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چکیده
منابع مشابه
A Rapid Combinatorial Library Synthesis of Benzazolo[2,1-b]quinazolinones and Triazolo[2,1-b]quinazolinones
Benzazolo [2,1-b]quinazolinones and triazolo[2,1-b]quinazolinones were synthesized in high yields by the condensation reaction of an aldehyde and a cyclic β-diketone with 2 - aminobenzimidazole, 2 - aminobenzothiazole or 1, 2, 4 - triazole derivatives in 1 - butyl - 3 -methylimidazolium bromide as an ionic liquid under classic heating conditions within 5-60 minutes.
متن کاملGene library synthesis by structure-based combinatorial protein engineering.
types of combinatorial libraries, such as random shuffling libraries and artificial alternative splicing libraries. The block shuffling and random point mutations can be introduced simultaneously by performing RMPCR under error-prone conditions. Most of the block sequences in the combinatorial libraries created by RM-PCR encode a long open reading frame and are suitable for protein selection ex...
متن کاملa rapid combinatorial library synthesis of benzazolo[2,1-b]quinazolinones and triazolo[2,1-b]quinazolinones
benzazolo [2,1-b]quinazolinones and triazolo[2,1-b]quinazolinones were synthesized in high yields by the condensation reaction of an aldehyde and a cyclic β-diketone with 2 - aminobenzimidazole, 2 - aminobenzothiazole or 1, 2, 4 - triazole derivatives in 1 - butyl - 3 -methylimidazolium bromide as an ionic liquid under classic heating conditions within 5-60 minutes.
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C O N T E N T S Forward Executive Summary Introduction Disease Prevalence Diabetes Mellitus Hypertension Risk Factor Prevalence Cigarette Smoking Physical Activity Obesity Cholesterol Alcohol Consumption Angina Awareness of Cancer Screening Breast Cancer Screening Cervical Cancer Screening Survey Response Survey Methodology References Annexes Annex A: Detailed Tables Annex B:Main Findings of Na...
متن کاملCurrent Status of Virtual Combinatorial Library Design
Combinatorial compound libraries have become an established research tool for finding molecules with desired properties. This review gives an overview on the current status of methods, techniques and design processes for combinatorial libraries. Recent developments include the sequential and parallel use of multiple sophisticated design criteria to select suitable molecules. Diversity measures,...
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ژورنال
عنوان ژورنال: Journal of Combinatorial Chemistry
سال: 1999
ISSN: 1520-4766,1520-4774
DOI: 10.1021/cc9900192